Clinical Study
A prospective, randomized, controlled multicentre trial evaluated Abilar 10% resin salve in 37 patients with severe grade II–IV pressure ulcers across 11 primary care hospitals. Participants were randomized to receive either the resin salve (n=13) or a standard "modern" treatment consisting of sodium carboxymethylcellulose hydrocolloid polymer, with or without ionic silver (n=9). Dressings were changed daily for infected or discharging wounds, or every third day for clean wounds. The study followed patients for 6 months, with wound progress monitored monthly through digital photography and planimetric analysis of width, length, and depth.
Key Findings
94% of the ulcers (17 of 18) treated with Abilar achieved complete healing within 6 months, compared to only 36% (4 of 11) in the control group (p = 0.003). The speed of healing was significantly faster in the resin group, with the superior effect of the salve becoming statistically evident after three months of treatment (p = 0.013). Additionally, bacterial cultures from the ulcer area became negative significantly more often within the first month in the resin group compared to the control group.
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Sipponen A, Jokinen JJ, Sipponen P, Papp A, Sarna S, Lohi J. Beneficial effect of resin salve in treatment of severe pressure ulcers: A prospective, randomized and controlled multicentre trial. British Journal of Dermatology. 2008 May;158(5):1055–62. doi:10.1111/j.1365-2133.2008.08461.x PubMed PMID: 18284391.
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